ABSTRACT
Upper gastrointestinal bleeding [UGIB] is a common medical condition that presents with hematemesis [vomiting of blood or coffee ground -like material] and/or melena [black, tarry stools]. Gastroduodenal ulcer disease, erosive esophagitis, esophagogastric varices, and erosive gastritis/duodenitis account for most of the cases. Ectopic varices are varices develop at sites other than the esophagus and stomach for example duodenal, rectal, and peristomal varices. Ectopic varices are relatively rare; however, approximately 5 percent are related to gastrointestinal bleeding. Duodenal variceal bleeding is a rare cause of gastrointestinal bleeding. Here we report a case of UGIB due to duodenal varices in a 44-year-old woman who admitted to the hospital because of melena, nausea, and vomiting from 3 weeks earlier. Two esophagogastroduodenoscopic examination and one colonoscopic examination were normal. Computed tomography [CT] of the abdomen revealed ectopic varices in the duodenum. Endoscopic cyanoacrylate was injected and bleeding was controlled. The patient did not experience rebleeding after one month
ABSTRACT
Gastrointestinal tract candidiasis is a common infection seen in immunocompromised hosts but occurs most frequently in esophagus. Candidiasis of the stomach and the small intestine is unusual. Herein we describe a 60-year-old woman with a history of diabetes mellitus and hypertension who presented to our hospital with melena, hematemesis, and confusion. She had taken ibuprofen since 2 weeks before the admission. In endoscopic evaluation multiple black and necrotic gastric ulcers in incisura and antrum with active bleeding and one clean base ulcer in the bulb of duodenum was seen. Amphotericin B was started because of highly suspicion to candida or mucormycosis infection. She was discharged from the hospital with well condition. Results of pathological evaluation confirmed candida associated gastric ulcer
ABSTRACT
Background: Employees are considered as an at-risk group for obesity and its adverse outcomes, particularly cardiovascular diseases [CVD]. The present study was conducted to assess the correlation of obesity indices with CVD risk factors among a group of medical university employees in Zahedan city, southeast of Iran
Methods: This cross-sectional study recruited 211 healthy employees of Zahedan University of Medical Sciences during October 2015. Obesity indices including body mass index [BMI], waist circumference [WC], waist to hip ratio [WHpR], and waist to height ratio [WHtR] were measured in accordance to the standard criteria. Fasting blood glucose [FBG], blood lipids, and blood pressure were also measured
Results: Women had significantly higher values of weight, WC, WHpR, and FBG than men [P < 0.05]. Bivariate analysis showed that those with BMI, WC, or WHtR higher than the cut-off-point levels had significantly higher serum levels of blood parameters and blood pressure compared to normal participants, respectively. BMI and WC had significant positive correlation with all parameters except with high density lipoprotein-cholesterol; these correlations were slightly stronger for WC compared to BMI. However, the correlation of WHpR and WHtR with metabolic parameters was weak
Conclusions: BMI and WC had an almost moderate correlation with CVD risk factors among the participants. Therefore, using WC along with BMI is suggested as the preferred method for assessment of CVD risk factors
ABSTRACT
Background: Previous researches reported inconclusive findings on the interaction of Helicobacter pylori [H.pylori] infection with body indices, although, most of these studies used body mass index [BMI] to assess such an association. The aim of this study was to investigate the association of H.pylori seropositivity with anthropometric indices as well as blood pressure [BP] among a group of young population in Zahedan, a city in south-east of Iran
Methods: A total of 363 undergraduate students participated in this cross-sectional study, in 2014. Serum IgG antibodies against H.pylori were measured and the cut-off level of antibody titers more than or equal to 20 was considered as H.pylori positive. Anthropometric indices and BP were measured using standard protocols
Results: Data analysis indicated that H.pylori seropositivity was equal to 45.7%. H.pylori positive participants had significantly lower mean values of BMI [P = 0.01], waist circumference [WC], and waist to height ratio [WHtR] which was marginally significant [P = 0.05] compared to H.pylori negative participants. No significant differences were found in waist to hip ratio [WHpR], as well as systolic blood pressure [SBP] and diastolic blood pressure [DBP] between the two groups. Although, after adjustment for confounding factors, higher values of BMI [OR = 1.12, 95% CI = 1.003-3.2] and WHtR [OR = 1.04, 95% CI = 1.001-2.71] were positively correlated with higher odds of H.pylori positivity
Conclusions: H.pylori positivity was correlated with higher BMI and WHtR after adjusting for other variables, but no correlation was observed for WC, WHpR, or BP among a group of young undergraduate students in south-east of Iran